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Research and Innovation

Gustave Roussy's medical-scientific programmes

Gustave Roussy’s Medical and Scientific Programs

At the heart of interdisciplinary cancer care, from before to after cancer, for every patient

As part of its “Gustave Roussy 2030” strategic plan, the Institute has identified flagship programs aimed at tangibly transforming care for people with cancer through research. These programs draw on both the clinical research and the translational and basic research conducted by Gustave Roussy’s teams.

These medical-scientific programs are based on exploratory research that has generated well-substantiated hypotheses and rely on large-scale cohorts, sample profiling using high-throughput platforms, and the mathematical analysis of the massive amounts of data generated by this profiling.

Institutional Programs

Identify situations of increased risk for certain cancers and implement a personalized prevention program in collaboration with primary care physicians.

To create a care structure dedicated to managing sequelae and diagnosing the risk of complications through individualized medical follow-up.

Accelerate the development of immunotherapy and make it available to as many patients as possible.

Identify and understand the mechanisms of resistance to cancer treatments and offer new treatment options to patients.

To better understand the role of genetics in pediatric cancers

To improve CAR-T cell therapies to make them more effective, longer-lasting, and better suited for treatment-resistant cancers.

Gaining a better understanding of the mechanisms underlying the onset, progression, and treatment resistance of pancreatic cancer.

National Programs

The Value of Liquid Biopsy in Lung Cancer

Organoids to predict treatment response in gastrointestinal cancers

Studies the role of the gut microbiota in response to immunotherapies

An innovative immunoradiotherapy to spare the immune system

Characterizing the biological characteristics of patients and their tumors to develop new immunotherapies

Working together to develop innovative new treatments to fight pediatric cancers.

An integrated translational oncology research program focused on epigenetics

Its goal is to create the first integrated ecosystem focused on immunology, bringing together experts from various disciplines: cancer, autoimmune diseases, and immunotherapy.

The MONO-CHEM research project aims to develop a new generation of cell therapy.  

Gustave Roussy participates in three national cohorts: CANTO, E3N Générations, and COBLAnCE. These are key tools that help advance research.

European Programs

A European study on first-line treatment for metastatic kidney cancer.

A European program to better predict response to and resistance against antibody-drug conjugates.

Better assessing lung cancer risk to personalize prevention

The European Union supports scientific excellence through several funding mechanisms, including grants from the European Research Council (ERC) and the Horizon Europe framework program.