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List of research teams

EpiRad: Understanding the Long-Term Effects of Cancer Treatments and Radiation Exposure in Children, Adolescents, and Young Adults

  • Logo Université Paris-Saclay
Thematic(s)
Genetics / Genomics, Pediatric Oncology, Public Health & Epidemiology
Attachment unit
U1018 - Research Center for Epidemiology and Population Health (CESP)
Manager(s)
Rodrigue Allodji, Neige Journy
Institutional connection

Gustave Roussy, Inserm, Paris-Saclay University, UVSQ

Summary

Childhood and Adolescent Cancer: growth & development, organ function, fertility & reproduction, carcinogenesis, psychosocial

The EpiRad team studies the long-term health effects of ionizing radiation and cancer treatments, primarily in children, adolescents, and young adults. Its goal is to better understand the clinical, dosimetric, biological, and socioeconomic determinants of iatrogenic complications in order to improve prevention, personalized treatment, and the organization of long-term follow-up.

The research is organized around four complementary areas:

  • the evaluation of late effects associated with advances in cancer therapy, including radiation therapy, radioisotopes, and innovative drugs

  • the identification of markers of genetic susceptibility and accelerated aging

  • the development of advanced statistical methods and risk prediction tools

  • the evaluation of long-term surveillance strategies, adherence to recommendations, and new communication tools for survivors

The team draws on unique research infrastructures, notably the FCCSS (French Childhood Cancer Survivor Study) cohort, as well as the VENUS, ANGIO, HARMONIC, and HORUS cohorts. These resources have demonstrated the persistence, several decades after treatment, of risks for secondary cancers, cardiovascular disease, ototoxicity, and other conditions.

EpiRad is also developing innovative methodological approaches that incorporate measurement uncertainties, voxel-based analyses, and artificial intelligence to fully exploit three-dimensional dose distributions and refine predictive models. At the same time, the GeneFCCSS program combines exome sequencing, transcriptomics, and molecular epidemiology to identify rare variants, biomarkers, and polygenic risk scores associated with late complications.

EpiRad’s work has a major impact on clinical guidelines, screening strategies, and personalized medicine.

Team members

  • Rodrigue ALLODJI - Team Leader

    Researcher and equivalent positions, Inserm

     

    Neige JOURNY - Team Leader

    Research Associate and Equivalents, Inserm

     

    ABALO Kossi Dovene

    Researcher and equivalent positions, Uppsala University – Sweden

     

    ADAM DE BEAUMAIS Tiphaine

    Hospital Physician, Gustave Roussy

     

    AHO GLELE Detongnon Rivalin Gilardi

    Ph.D. Candidate, Paris-Saclay University

     

    AIT ALI Mohamed

    Ph.D. student, Paris-Saclay University

     

    BALDE Mamadou Hady

    Research Engineer or equivalent, Inserm

     

    DE VATHAIRE Florent

    Emeritus Research Director, Inserm

     

    Charlotte Demoor

    Hospital Physician, Angers University Hospital

     

    FIEVET Alice

    Hospital Physician, Gustave Roussy

     

    Brice FRESNEAU

    Hospital Physician, Gustave Roussy

     

    Alfred Arnaud GBETCHEDJI

    Research Engineer or equivalent, National Authority for Radiological Safety and Radiation Protection, Benin

     

    GNANGNON, Freddy

    Hospital Physician, Faculty of Health Sciences, University of Dabomey-Calavi

     

    HADDY Nadia

    Research Fellow or equivalent, ANSM

     

    Ons HAMZAOUI

    Ph.D. Candidate, Paris-Saclay University

     

    HOARAU Pauline

    Design Engineer or equivalent, Gustave Roussy

     

    KARIMI Maryam

    Research Associate or equivalent, Paris-Saclay University

     

    KHEDDAM Dihya

    Engineering Assistant or equivalent, Gustave Roussy

     

    Céline Khouri

    Hospital Physician, Gustave Roussy

     

    KOUTANGNI Tatiana

    Design Engineer or equivalent, Gustave Roussy

     

    Laura LENEZ

    Hospital Physician, Gustave Roussy

     

    MANSOURI Imene

    Research Fellow or equivalent, AGENCE DE BIOMEDECINE

     

    MARCHI Joffrey

    Ph.D. Student, Aix-Marseille University

     

    MEILLAN Nicolas

    Ph.D. Candidate, APHP

     

    Carole Rubino

    Researcher and equivalent positions, Inserm

     

    SCHWARTZ Boris

    Research Engineer or equivalent, Gustave Roussy

     

    Allison Singier

    Postdoctoral Fellow, Gustave Roussy

     

    Vincent Souchard

    Research Engineer or equivalent, Gustave Roussy

     

    TEINTURIER, Cécile

    Hospital Physician, APHP

     

    Giao Vu-Bezin

    Design Engineer or Equivalent, Gustave Roussy

Contacts

Phone
Administrator: 01.42.11.41.40
Location: Gustave Roussy Institute