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Experimental and Translational Pathology
Joint Service Unit
US23 – AMMICa
Platform Type
Technology Platform
Scientifi Director
Prof. Cécile Badoual
Research Areas
Spatial Analysis, Cell Imaging, Multiplex Imaging, Microscopy, Multi-omics, Modeling, Proteomics, Single-Cell Analysis, Transcriptomics
Abstract
The Platform for Experimental and Translational Pathology (PETRA), led by Professor Cécile Badoual, is dedicated to performing a full range of in situ morphological and molecular analysis techniques, primarily in connection with clinical trials and precision medicine protocols led by Gustave Roussy, as well as with numerous national and international multicenter research programs. It is one of the research support and assistance platforms within the AMMICa unit (Molecular Analysis, Modeling, and Imaging of Cancer), established in January 2015.
It is equipped with a comprehensive range of instruments that enable it to perform all techniques in conventional histology, multiplex immunohistochemistry, and image analysis, and benefits from the expertise of Gustave Roussy’s anatomical pathologists. It offers proteomics and spatial transcriptomics techniques, thanks to support from the Paris Saclay Cancer Cluster (PSCC), and has helped strengthen, promote, or establish academic and industrial partnerships and collaborations.
The platform provides project management services, including personalized support throughout the planning and execution of projects. PETRA handles all morphological analyses of tissue or cell samples—from human and animal models (PDX and organoids/tumoroids)—from the pre-analytical stage through to the analyses themselves, as well as the digitization and interpretation of slides.
PETRA provides scientific, technical, and regulatory expertise in collaboration with a multidisciplinary team.
The platform is a member of the Île-de-France histology platform network (Rés’Hist) and has been awarded the IBiSA platform certification. The platform has been ISO 9001 certified since 2016.
ISO 9001:2015 Certification
Services Offered
The PETRA platform at Gustave Roussy brings together expertise ranging from pre-analytical to post-analytical processes for the study of human and animal samples. Upstream, it handles paraffin embedding, sectioning of frozen or fixed tissues, the preparation of TMA, and the preparation of cell clusters or organoids. The analytical phase includes single- or multi-marker immunohistochemistry (chromogenic or fluorescent), in situ hybridization/FISH, and spatial profiling in transcriptomics and proteomics. Downstream, the platform offers high-throughput image digitization using various scanners and analysis of these images using specialized software. Together, these steps form an integrated workflow that enables detailed characterization of tissues and biomarkers to support oncology research and diagnosis.
The PETRA platform at Gustave Roussy primarily offers expert support for designing and ensuring the safety of experimental projects in histology and spatial biology. It advises teams on selecting the techniques best suited to their scientific objectives, whether for protein or transcriptomic analyses. PETRA gets involved early on to optimize the setup of experiments, from sample selection and preparation to panel definition. It also validates labels (antibodies, probes) and protocols to ensure the robustness and reproducibility of results. Depending on the needs, PETRA guides teams toward the most relevant approaches (immunohistochemistry, FISH, RNAscope, Merscope, Visium, GeoMx). This expertise helps optimize data quality and ensure the success of projects.
Contact Us
If you are considering commissioning an analysis from us, please contact us to learn more about available options, define the scope of work, and obtain a quote: contact-petra@gustaveroussy.fr
If you wish to submit a more detailed request, you can use this contact form: https://forms.cloud.microsoft/e/3KLifURqKu?origin=lprLink
Once your project has been reviewed, you will receive a response within a maximum of 10 days, along with a proposed date for a presentation. PETRA will facilitate the connection with the genomics and data platform if the project requires it.
Team
Cecile BADOUAL - Platform Scientific Director
University Professors and Hospital Practitioners
Employer: Gustave Roussy
BANI Mohamed-Amine - Platform Scientific Director
Hospital Practitioners
Deputy Platform Director
Employer: Gustave Roussy
BAWA Olivia
Research Engineer or equivalent
Employer: Gustave Roussy
BORDELET Laeticia
Research Technician or equivalent
Employer: Gustave Roussy
CAMARA CLAYETTE Valérie
Research Engineer or equivalent
Employer: Gustave Roussy
CAMUS Lily
Research Technician or equivalent
Employer: Gustave Roussy
CHANSAVOIR Betty
Research Technician or equivalent
Employer: Gustave Roussy
CHERON Maria Laura
Research Technician or equivalent
Employer: Gustave Roussy
DUTERTRE Charles Antoine
Other status, including apprentice
Civil servant researcher
Employer: Inserm
EDMOND Elodie
Research technician or equivalent
Employer: Gustave Roussy
GODEFROY Karine
Research technician or equivalent
Employer: Gustave Roussy
MARTY Virginie
Design Engineer or equivalent
Employer: Gustave Roussy
RATHASKRISHNAN Adsaya
Research technician or equivalent
Employer: Gustave Roussy
ROLLAND Mailys
Research technician or equivalent
Employer: Gustave Roussy
SIGNOLLE Nicolas
Research Engineer or equivalent
Employer: Gustave Roussy
ZEARAMANE Anjeli
Other status, including apprentice
Employer: Gustave Roussy
Key Publications
Contact
- Address
-
B2M
114 Edouard-Vaillant Street
94 805 Villejuif Cedex, France
Platform Operations Manager
Cécile Badoual
cecile.badoual@gustaveroussy.fr
