Biography - Lisa Derosa

Biography

Lisa Derosa

Dr. Lisa Derosa is a clinical oncologist and university associate professor - Hospital Practitioner (MCU-PH) in clinical immunology at Paris-Saclay University, and a hospital practitioner in the Department of Medical Oncology at Gustave Roussy.

After earning her degree in medical oncology in Italy, she moved to France in 2016. She then pursued the European University Diploma in Translational and Clinical Cancer Research (DUERTECC) at Paris-Saclay University, and that same year joined the INSERM U1015 unit, affiliated with that university, with the support of a grant from the Philanthropia Foundation.

She earned her Ph.D. in clinical immunology from Paris-Saclay University in 2019. In 2022, she was appointed clinical director of the ClinicObiome program at Gustave Roussy, an organization dedicated to therapeutic interventions focused on the microbiome in cancer patients.

In 2023, she became an Associate Professor (MCU-PH) in immunology and a permanent member of INSERM Unit U1367. In 2024, she successfully defended her habilitation to supervise research (HDR).

Dr. Derosa’s work has significantly contributed to advances in cancer immunology and immunotherapy, particularly by highlighting the central role of the gut microbiota in the response to anticancer treatments. Her research has demonstrated the detrimental impact of antibiotics on the efficacy of immunotherapy and has led to the development of diagnostic approaches for gut dysbiosis.

She is currently actively engaged in clinical translational research, aiming to integrate microbiota-focused interventions into personalized and innovative care for cancer patients.

In addition to her clinical and research activities, Dr. Derosa leads a course dedicated to the gut microbiota. She teaches in numerous training programs at Gustave Roussy and the Paris-Saclay University School of Medicine, contributing to the dissemination of knowledge and the training of both students and healthcare professionals.

Through her research and commitment to teaching, Dr. Derosa plays a key role in developing new therapeutic strategies against cancer, combining scientific innovation with a patient-centered approach based on the gut microbiome.

Her work has been recognized with numerous international awards, notably from the AACR, ASCO (five awards), ESMO (three awards), and European Urology, as well as the Gallet and Breton Prize from the National Academy of Medicine.

The complete list of her publications is available on Google Scholar (h-index: 50; over 18,300 citations).

More recently, she was named the recipient of the Robert Debré Prize for Medical Research, recognizing the excellence of her work and her commitment to research—particularly through the ClinicObiome program—and highlighting the growing recognition of the role of the microbiome in oncology.